Bioinformatics approach: A powerful tool for microRNA research

Bioinformatics is an important approach for the management of biological data on a larger scale. It is basically an emerging interdisciplinary field of modern biotechnology that develops methods and softwares for an understanding of biological data. For data analysis or interpretations, bioinformatics utilizes in-silico approach to answering the biomedical questions using mathematical and statistical methods.1 The basic objective of bioinformatics approach is storage of extensive molecular biology data in database forms. These data must be assigned in a ways to give suitable meaningful information in different grades.1,2 As for example, GenBank nucleotide sequence information, etc. Another objective of bioinformatics approach is data analysis. As of BLAST to analyze a nucleotide sequence of the same type to design primers or probes for polymerase chain reaction technique, etc. However, the central objective of bioinformatics approach is to interpret extensive biomedical data, resulting to give meaningful biological information.1,2 So far, bioinformatics approach has got super success for the determination of nucleotide sequence alignment, gene expression prediction, prediction of protein structure, alignment of protein structure and also in studies of genome-wide association, assembly of the genome and also for modeling of evolution.1-3